Discover a world of possibilities with METHOCEL™ cellulose ethers

Pioneering Then, Innovating Now

Enhancing therapeutic performance while keeping pace with evolving regulatory and safety expectations is a constant pressure for drug developers, but it is key to unlocking next-generation therapies that better serve patients.

Our flagship portfolio of water soluble METHOCEL™ cellulose ethers — methylcellulose (MC) and hydroxypropyl methylcellulose (HPMC), is designed to put you in control of your formulations, enabling optimized drug release and safer therapeutics.

Step into the world of METHOCEL™ and see how it helps you tackle the challenges of modern formulations.

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KEY BENEFITS OF METHOCEL™ INCLUDE:
  • Successfully used for 75+ years
  • Rate-modifying hydrogel former with robust controlled release performance
  • Excellent rheology-modifier, binder, film-former, and water-retention agent
  • Highly soluble in cold water
  • Reversable thermo-gelation properties
  • Reverts to liquid form upon cooling
  • Available in low nitrite grades
  • Exceptional versatility and formulation flexibility
  • Successfully used for 75+ years
  • Rate-modifying hydrogel former with robust controlled release performance
  • Excellent rheology-modifier, binder, film-former, and water-retention agent
  • Highly soluble in cold water
  • Reversable thermo-gelation properties
  • Reverts to liquid form upon cooling
  • Available in low nitrite grades
  • Exceptional versatility and formulation flexibility
Key applications of METHOCEL™ include:
  • Controlled release
  • Coatings
  • Granulation binder
  • Nitrosamine mitigation
  • Solubility enhancement

Navigate a new era in drug development with METHOCEL™ cellulose ethers

In our whitepaper, we explore how METHOCEL™ HPMC can help drug developers unlock the full potential of a formulation. Download it now to uncover:

  • Which HPMC polymer characteristics drive optimal drug release performance
  • Proven strategies to fine-tune controlled release formulations
  • How low nitrite excipients can form part of a holistic mitigation strategy
  • Expert insights on how excipients can enhance therapeutic efficacy and safety

Master controlled release with METHOCEL™ excipients

As the first-ever HPMC excipient developed specifically for pharmaceutical use, METHOCEL™ set the standard for innovation in controlled release. It is available in a range of molecular weights and customized chemical substitutions, making it ideal for modulating the release of APIs in the body.

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Expert Formulation Insights: Controlled Release with HPMC

Looking for practical guidance on achieving consistent controlled release performance? Our formulators share proven strategies and tips for working with HPMC excipients in real-world applications.

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Futureproof formulations with award-winning low nitrite METHOCEL™

Awarded first place in the NIE new ingredient awards (Excipients/Non-Actives category), our low nitrite METHOCEL™ excipients help formulators reduce the risk of nitrosamine formation. This enables drug developers to mitigate one possible (but common) route of nitrosamine formation — the reaction between nitrites in excipients and vulnerable amines in APIs. Our Low Nitrite METHOCEL™ grades are designed to meet the highest standards of quality and safety, while providing the same reliability and performance as standard METHOCEL™.

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Partner with Roquette

At Roquette’s Health & Pharma Solutions Business Group, we help drug developers harness the benefits of METHOCEL™ cellulose ethers to unlock the full potential of their formulations, from maximizing therapeutic efficacy to ensuring patient safety.

 

Connect with our experts to start your journey today