METHOCEL™ Overview Brochure
Find out moreDiscover a world of possibilities with METHOCEL™
METHOCEL™ is Pharma Solutions’ premium family of water-soluble cellulose ethers for pharmaceutical innovation.
Unlike other water-soluble polymers, METHOCEL™ delivers multiple stand-out benefits, versatile properties and superior flexibility; including varying grades of methylcellulose (MC) or hydroxypropyl methylcellulose (HPMC) polymers. Our cellulose ethers are suitable for a number of pharmaceutical formulations – including those requiring controlled-release, granulation binders, tablet coating, drug layering, capsule shell formers and rheology-modifiers for solutions and suspension. The portfolio is backed by 70+ years of continuous production globally and deep polymer expertise.
Product benefits
- Successfully used for 70+ years
- Multi-functional application
- Rate-modifying hydrogel former with robust modified release performance
- Excellent rheology-modifier, binder, film-former and water-retention agent
- Highly soluble in cold water
- Reverse-thermo gelation properties
- Reverts to liquid form upon cooling
Learn how METHOCEL™ can improve your formulation.
Key applications
- Solubility enhancement
- Controlled release
- Coatings
- Granulation binder
** Available as CR (Controlled Release) grades with narrowed substitution and particle size from more reproducible and reliable controlled release performance.
+ Available as DC2 grades with optimized flow properties to allow greater throughput with less tablet variability while potentially eliminating granulation processes.
* Examples only and not representative of a complete list of recommended products or benefits.
METHOCEL™ Premium Products | Viscosity Grade, mPa*s | Nominal Methoxy Substitution | Nominal Hydroxypropoxyl Substitution | Recommended Applications |
|---|---|---|---|---|
E3 LV E5 LV E6 LV E15 LV E50 LV E4M** E10M** | 3 5 6 15 50 4,000 10,000 | 29% | 10% | Tablet Coating, Granulation, Drug Layering, Add Capsule Hard Shell Former Stabilizing Amorphous Drugs, Oral Thin Films Controlled Release, Oral Thin Films Add Suspension Stabilizer |
VLV F4 LV F5 LV F4M | 2.8 4 5 4,000 | 29% | 6% | Wet Granulation, Drug Layering, Tablet Coating, Add Capsule Hard Shell Former
Add Suspension Stabilizer |
K3 LV K100 LV**+ K4M** K15M** K100M**+ K200M** | 3 100 4,000 15,000 100,000 200,000 | 22% | 8% | Granulation Controlled Release |
A15 LV A4M | 15 4,000 | 29% | 0% | Granulation Viscosifying Solutions |
Connect with us
Ready to start your METHOCEL™ collaboration? Speak to one of our experts today.
We can help you along your product development process. Contact us to start your journey to success.
We can help you along your product development process. Contact us to start your journey to success.
