A cell-compatible methyl cellulose for biotech applications

METHONOVA™ is the latest addition to our renowned NovaMatrix® range, a trusted portfolio of biopolymers tailored for use in the biotechnology industry. Our METHONOVA™ methyl cellulose builds on decades of polymer science expertise and meets the exacting standards of NovaMatrix®, undergoing elaborate quality testing for bioburden and elemental impurities.

METHONOVA™ has a low fiber content, easing sterile filtration to create a highly purified product suitable for use in cell culture. Cytotoxicity testing ensures METHONOVA™ is compatible with cells. Our cutting-edge solution is responsibly sourced, and adheres to stringent product specifications, making it a preferred choice for high-quality biotechnology and bioprocessing applications.


METHONOVA™ is a plant-based, water-soluble biopolymer derived from cellulose, the most abundant polymer in nature. METHONOVA™ methyl cellulose is a natural carbohydrate composed of repeating anhydroglucose units. During manufacture, cellulose fibers are treated with a caustic solution, followed by methyl chloride treatment, yielding the methyl ether of cellulose. The fibrous reaction product is purified and ground to a fine powder.

Product benefits
  • Ease of sterile filtration
  • Cell compatibility, verified via cytotoxicity test to mammalian cells
  • Stringent quality standards
  • Outstanding viscosity stability during long-term storage
  • Water-solubility
  • Reverse thermo-gelation properties
  • Xeno-free formulation
Key applications

METHONOVA™ methyl cellulose is suitable for use in:

  • Cell culture assays
  • Stem cell protection
  • Cryopreservation and cell media
  • 3D bioprinting
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Specifications and Quality



Apparent Viscosity (2%, 20C)

Quality testing*


13-17 mPa*s

Cell compatibility (cytotoxicity to mammalian cells)

Elemental impurities


Fiber content


* Examples only and not representative of a complete list of all quality tests


METHONOVA™ methyl cellulose is manufactured under excipient cGMP requirements. It is certified to meet the respective monographs: USP (United States Pharmacopeia), EP/PhEur (European Pharmacopeia) and JP (Japanese Pharmacopeia).

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Do you have questions regarding METHONOVA™ or are you interested in buying the product? Get in touch!


Do you have questions regarding METHONOVA™ or are you interested in buying the product? Get in touch!